The Reinhardt Group

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  • Currently displaying 1 - 20 of 61 publications
Author(s)
Publication title
Journal Name
Publication year
Probing molecular and biophysical mechanisms of RNA and protein phase transitions with simulations and theory
PY Chew, R Collepardo-Guevara
Current Opinion in Structural Biology
(2025)
93
(doi: 10.1016/j.sbi.2025.103120)
Probing the Microscopic Behavior of PFOS Clustering and Adsorption at LNAPL Interfaces; a PFOS-Water-Cyclohexane System
K Sookhak Lari, A Reinhardt, AC Warden, JL Rayner, GB Davis
Environmental science & technology
(2025)
59
(doi: 10.1021/acs.est.5c01748)
Phase behaviour of multicomponent systems from computer simulations
PY Chew
(2025)
(doi: 10.17863/CAM.120276)
Recombinase-Controlled Multiphase Condensates Accelerate Nucleic Acid Amplification and CRISPR-Based Diagnostics.
A Homchan, M Patchsung, P Chantanakool, T Wongsatit, W Onchan, D Muengsaen, T Thaweeskulchai, M Tandean, T Sakpetch, S Suraritdechachai, K Aphicho, C Panchai, S Taiwan, N Horthongkham, T Sudyoadsuk, A Reinhardt, C Uttamapinant
J Am Chem Soc
(2025)
147
(doi: 10.1021/jacs.4c11893)
Chemically Informed Coarse-Graining of Electrostatic Forces in Charge-Rich Biomolecular Condensates.
A R Tejedor, A Aguirre Gonzalez, MJ Maristany, PY Chew, K Russell, J Ramirez, JR Espinosa, R Collepardo-Guevara
ACS central science
(2025)
11
(doi: 10.1021/acscentsci.4c01617)
Models and simulations of structural DNA nanotechnology reveal fundamental principles of self-assembly.
A Cumberworth, A Reinhardt
Chemical Society Reviews
(2025)
54
(doi: 10.1039/d4cs01095g)
Chemically-informed coarse-graining of electrostatic forces in charge-rich biomolecular condensates
A Tejedor, AA Gonzalez, J Maristany, PY Chew, K Russell, J Ramirez, J Espinosa, R Collepardo-Guevara
(2024)
(doi: 10.1101/2024.07.26.605370)
Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation.
K Brown, PY Chew, S Ingersoll, JR Espinosa, A Aguirre, A Espinoza, J Wen, K Astatike, TG Kutateladze, R Collepardo-Guevara, X Ren
Cell Rep
(2024)
43
(doi: 10.1016/j.celrep.2024.113997)
A streamlined molecular-dynamics workflow for computing solubilities of molecular and ionic crystals
A Reinhardt, PY Chew, B Cheng
Journal of Chemical Physics
(2023)
159
(doi: 10.1063/5.0173341)
Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation.
K Brown, PY Chew, S Ingersoll, JR Espinosa, A Aguirre, A Espinoza, J Wen, K Astatike, TG Kutateladze, R Collepardo-Guevara, X Ren
Cell Reports
(2023)
42
(doi: 10.1016/j.celrep.2023.113136)
A streamlined molecular-dynamics workflow for computing solubilities of molecular and ionic crystals
A Reinhardt, PY Chew, B Cheng
(2023)
(doi: 10.48550/arxiv.2308.10886)
Quantitative real-time in-cell imaging reveals heterogeneous clusters of proteins prior to condensation.
C Lan, J Kim, S Ulferts, F Aprile-Garcia, S Weyrauch, A Anandamurugan, R Grosse, R Sawarkar, A Reinhardt, T Hugel
Nature Communications
(2023)
14
(doi: 10.1038/s41467-023-40540-2)
Aromatic and arginine content drives multiphasic condensation of protein-RNA mixtures
PY Chew, JA Joseph, R Collepardo-Guevara, A Reinhardt
Biophysical Journal
(2023)
123
(doi: 10.1016/j.bpj.2023.06.024)
Aromatic and arginine content drives multiphasic condensation of protein–RNA mixtures
PY Chew, J Joseph, R Collepardo-Guevara, A Reinhardt
(2023)
(doi: 10.1101/2023.04.05.535720)
Physical determinants of multiphase organisation in multi-component protein/RNA condensates
PY Chew, JA Joseph, R Collepardo-Guevara, A Reinhardt
Biophysical Journal
(2023)
122
(doi: 10.1016/j.bpj.2022.11.1672)
Thermodynamic origins of two-component multiphase condensates of proteins.
PY Chew, JA Joseph, R Collepardo-Guevara, A Reinhardt
Chem Sci
(2023)
14
(doi: 10.1039/d2sc05873a)
Signaling by cluster formation investigated with single-molecule fluorescence in living cells
S Weyrauch, C Lan, J Kim, S Ulferts, F Aprile-Garcia, A Anandamurugan, R Grosse, R Sawarkar, A Reinhardt, T Hugel
EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS
(2023)
52
Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation
K Brown, PY Chew, S Ingersoll, J Espinosa, A Aguirre, T Kutateladze, RC Guevara, X Ren
(2022)
(doi: 10.1101/2022.12.26.521954)
Phase diagrams—Why they matter and how to predict them
PY Chew, A Reinhardt
Journal of Chemical Physics
(2022)
158
(doi: 10.1063/5.0131028)
Simulations of DNA-origami self-assembly reveal design-dependent nucleation barriers
A Cumberworth, D Frenkel, A Reinhardt
Nano Letters: a journal dedicated to nanoscience and nanotechnology
(2022)
22
(doi: 10.1021/acs.nanolett.2c01372)
Yusuf Hamied Department of Chemistry
Lensfield Road
Cambridge
CB2 1EW
T: +44 (0) 1223 336300
enquiries@ch.cam.ac.uk
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